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Arizona Oncology
Arizona Oncology

Are You High Risk for Developing Colon Cancer?

Home > Blog > Are You High Risk for Developing Colon Cancer?

October 30, 2018
Risks For Colon Cancer

A Simple Test Could Tell You!

Cancer researchers from Johns Hopkins have concluded that some patients may develop colon cancer due to two specific digestive bacteria that form a film on the colon. According to the study paper, which was published December 2015 inScience magazine, these two types of bacteria invade the protective mucous layer of the colon and create a small ecosystem, including nutrients the bacteria need to survive, causing chronic inflammation and subsequent DNA damage that supports tumor formation. These findings also seem to add to the growing evidence that gut bacteria is more influential on our immune system than we may realize.

The two bacteria the doctors found are known as Bacteroides fragilis and Escherichia coli (or E. coli). The B. fragilis strain, called ETBF, appears to cause inflammation in the colon, while the E. coli strain causes DNA mutations.

Also, the bacteria was linked to patients without a family history of colon cancer. Cancers such as these–where there is no genetic tie–are known as sporadic cancers. Only 5-10% of cancers are considered heredity, meaning the remaining 90-95% are considered sporadic.

What does this mean for colon cancer treatment?

Knowing that the presence of these bacteria may put someone at a higher risk of developing colon cancer may make it possible to screen earlier and monitor those who are found to have them in their digestive tract. Determining whether both of these bacteria are present may require only a simple and painless stool test.

Better Strategies to Reduce the Risk of Colon Cancer

While it’s impossible to completely eliminate these bacteria, there are things you can do to reduce the likelihood that this combination of bacteria will grow in your colon. Two strategies that may help reduce the risk of developing colon cancer in the future may include:

  1. Targeted antibiotics and probiotics. Both of these are two possibilities that could be beneficial in promoting healthy bacteria to chase away the harmful bacteria in the colon. Since antibiotics can damage both good and bad bacteria, taking a probiotic with it can help replenish the good bacteria and restore balance to your system. Probiotics can also be taken even if you are not taking an antibiotic. It is always best to talk with a qualified professional before adding a probiotic to your regimen.
  2. Eating a diet rich with gut healing properties. Certain foods can be helpful in reducing the risk of colon cancer and other types of cancers as well. Gut-healing foods typically fall under two categories: probiotic foods and prebiotic foods.
    1. Probiotic foods – Contain live bacteria, and include foods such as plain, low-fat yogurt (preferably organic), kefir (a yogurt-like drink), kombucha tea, and fermented vegetables like sauerkraut and kimchi.
    2. Prebiotic foods – Feed the bacteria in your gut so they can grow and repopulate, include whole grains, oatmeal, soy beans, garlic, fruits and vegetables (like bananas, onions, and asparagus).

Currently, colonoscopies are the standard of care for monitoring the formation of precancerous tumors, called polyps. According to the study, however, adding a stool analysis to the screening process could provide an opportunity for an earlier and less-invasive way to intervene before the bacteria take over the colon. Although this isn’t a cure, it will make an impact on how colon cancer is detected. 

If you have any concerns please visit your doctor for a colon cancer screening. If you are located in Arizona, there are many resources nearby for you to access colonoscopies. The Colon Cancer Coalition provides a tool that allows you to find a screening location near to you.

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