Arizona Oncology - The US Oncology Network

Know Your Risk About Breast Cancer - Dr. Mike Janicek, Gynecologic Oncologist, speaks about Genetic Testing on EVB live channel 12.

5/15/2013

Angelina Jolie's double mastectomy has sparked a lot of questions about genetic testing. Hear from a woman who went through what Jolie did and Dr. Mike Janicek about the genes BRCA1 and BRCA2 and what you need to know to make an informed decision.

Fast Facts about Genetic Risks for Cancer:
-According to NCCN guidelines, any woman with epithelial ovarian, fallopian, or primary peritoneal cancer should be tested for BRCA mutations.
-Inherited cancers often occur at younger ages than sporadic cancers.
-Endometrial cancer is often the sentinel malignancy in women with Lynch (HNPCC) Syndrome.
-Up to 15% of oncology patients may have an inherited mutation that puts them at higher risk of cancer recurrence and at risk for second malignancy.
-BRCA mutations are present in as many as 1 in 40 Ashkenazi individuals in the general population.
-Cancer-causing mutations can be inherited from the mother or father.
-There are several cancers that could be caused by a gene mutation including breast, ovarian, fallopian tube, peritonea, stomach, colon, brain tumors, thyroid, kidney, melanoma, prostate, pancreatic and others.
-Both women and men can carry a genetic mutation in the cancer-causing genes.